Clinical trials fail when they don't fit real lives

Pafira helps life science teams capture meaningful patient data without disrupting daily life — turning everyday signals into compliant, decision-ready evidence.

Not by adding complexity. By removing the friction that causes trials to stall.

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The problem

The science is rarely the issue

Clinical trials don't slow down because teams lack rigor.

They slow down because participation is hard to sustain.

  • Patients are asked to reshape their lives
  • Sites chase incomplete or inconsistent data
  • Sponsors wait too long to see what's really happening

The result: delayed decisions, recruitment failure, and avoidable risk.

Clinical trial participant
Paul Little

"For a long time, I believed the equation was simple: science plus money equals new drugs. What we forget is the human element."

— Paul Little Co-founder
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The Patient App

The Patient App that turns participation into usable trial data

Turn everyday moments into high-quality study data. Pafira's patient app makes it easy for participants to report outcomes, stay on schedule, and share biometrics—so your team gets cleaner, more complete datasets with less site burden.

Trials fail when participation becomes a second job. The app is built to fit into a patient's day: simple screens, minimal effort, and clear feedback—without sacrificing study rigor.

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Pafira Patient App
Track the patients mood
Biometrics data collection
Sleep can impact results
Keep engagement up
Reminders and push notifications
The Pafira team
The Pafira approach

Design trials around people — without weakening standards

Pafira is an experience-first ePRO / eCOA platform built for hybrid and virtual studies.

We make it easier for patients to report consistently, while ensuring sponsors and sites receive structured, validated, and auditable data they can trust.

The human layer is not an add-on. It's the starting point.

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How it works

Signals in seconds. Evidence you can stand behind.

Adaptive reporting

Reduces daily burden for patients

AI-assisted validation

Flags issues at the moment of entry

Automated alerts

Reminders and anomaly detection prevent drift

Shared audit trail

Keeps sites, sponsors, and monitors aligned

Problems are caught early — not weeks later in data cleaning.

For patients

  • ✓ Less disruption to daily life
  • ✓ Clear, simple reporting
  • ✓ Fewer corrections and follow-ups

For sites

  • ✓ Fewer data queries
  • ✓ Fewer in-person touchpoints
  • ✓ Less manual reconciliation

For sponsors & CROs

  • ✓ Earlier signal detection
  • ✓ Leaner monitoring
  • ✓ One consistent source of truth across teams

For decision-makers

  • ✓ Shorter indecision windows
  • ✓ Clearer evidence of study readiness
Compliance

Built for compliance, not workarounds

Investor- and regulator-ready by design.

Pafira is built with:

  • Centralised audit trails
  • Clean exports to EDC and SDTM-ready mappings
  • GDPR-first data handling
  • Transparent AI usage that supports — not obscures — submissions

No spreadsheet gymnastics.
No black boxes.

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Built for compliance, not workarounds — Pafira compliance architecture
FAQ

Frequently asked questions

Short answers for the questions investors ask most often.

Dynamic validation, automated reminders, and anomaly alerts flag issues before protocol deviations surface, shrinking cycle times and avoiding costly rework.

We're prioritising CNS and rare disease indications where daily patient sentiment is critical, before expanding to oncology and cardiometabolic trials.

Subscription tiers scale with cohort size and feature set, with volume-based pricing for sponsors and preferred terms for CRO partners.

Standard connectors ship for leading EDC and data lake platforms (Medidata Rave, Veeva, Snowflake). Site-specific integrations are supported via our API toolkit.

No. AI supports monitoring and scheduling; the submitted dataset is always the validated, human-readable record with full lineage.

We cut the legal loop short with standard DPAs, DPIA templates and privacy-by-design architecture. Sponsors see only what they're entitled to.

For investors

Pafira is building the data layer that makes hybrid and virtual trials viable at scale.

Are you interested gaining the pafira benefits?
Become a invester and partner in the development.

Download our invester brief
Pafira Investor Brief

Built with passion for the problem

Paul Little Paul Little

Drug development leader with decades of experience running clinical trials — and seeing first-hand how misaligned designs slow them down.

Ditte Høyer Ditte Høyer

With 20+ years' experience leading drug-development—he understands first-hand why trials are slow, costly and often mis-aligned with patient needs.

Mathias Mosel Mathias Mosel

With 20+ years' experience leading drug-development—he understands first-hand why trials are slow, costly and often mis-aligned with patient needs.

Mikkel Schrøder Mikkel Schrøder

With 20+ years' experience leading drug-development—he understands first-hand why trials are slow, costly and often mis-aligned with patient needs.

Rasmus Mosel Rasmus Mosel

With 20+ years' experience leading drug-development—he understands first-hand why trials are slow, costly and often mis-aligned with patient needs.

Better trials start with better participation

New therapies don't fail because the science isn't strong enough. They fail when trials don't fit real lives.

Pafira exists to close that gap — between scientific ambition and human reality.

If you're designing a study, facing recruitment challenges, or rethinking how trials should work in a modern healthcare system, we should talk.

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